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Toshihiro Kawamoto, M.D, Ph.D.
Curriculum Vitae
Recent Publications
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Toshihiro KAWAMOTO, M.D., Ph.D.
Professor of Environmental Health
Mailing address:
Iseigaoka 1-1, Yahatansihi
Kitakyushu, Fukuoka 807-8555
JAPAN
Telephone:
Office: :81-(0)93-691-7429
Fax: 81-(0)93-691-9341
Affiliations:
Member, University of Occupational and Environmental Health
Councilor of the Japanese Society for Hygiene
Councilor of Japan Society for Occupational Health
Member of International Commission on Occupational Health
Clinical/Research interest:
1. Genetic factors involved in the
alcohol drinking preference and toxicity. Individual differences in alcohol
preference are clearly genetically determined, which may translate into a
genetic predisposition for alcohol abuse and alcoholism. Specific genes
responsible for the increased or decreased susceptibility to alcohol abuse
remain largely unknown. Our laboratory studies the role of aldehyde
dehydrogenase 2 (ALDH2), as genetic factors associated with
alcoholism--including toxicity, carcinogenesis, abuse, and drinking
preference. Experimental approaches include transgenic mouse lines.
2. We study the relationship between individual
susceptibility to environmental hazardous chemicals and the genetic
polymorphisms of drug-metabolizing enzymes from the changes of metabolism and
excretion ratios by the genotypes of the enzymes.
3. Accoding to the changes in life-style, it is said that
more than 80% of our daily lives are spent indoors, especially, in developed
countries. Therefore, the interest for indoor air quality has been increasing
year by year. We have been studying indoor pollution by NO2, formaldehyde and
VOCs from kerosene heaters which were widely used during winter in Japan
for room heating. And the monitoring of indoor formaldehyde concentration and
other VOCs concentration in newly built house is continued. The indoor
pollution by formaldehyde from cigarette smoking is also studied under
ventilating and poor ventilating conditions in the model room. Finally, we
are trying to evaluate the health effects of indoor pollutants
Teaching:
Professional Program:
Hygiene, Occupational Health
Graduate Program:
Biological Monitoring, Molecular Epidemiology,
Quality Control, Exposure Assessment, Individual Susceptibility
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