1. Name, Degree
   Masaharu Ikeda, MD, PhD

2. Key Words
   Health Promotion, Hypertension, Lifestyle-related Diseases, Exercise Training, Stress and Cardiovascular Disease

3. Selected Publicaion
   
   1. Ohta, M., Nanri, H., Matsushima, Y., Sato, Y., Ikeda, M. Blood pressure-lowering effects of lifestyle modification: possible involvement of nitric oxide bioavailability. Hypertens Res,28,779-786,2005
   2. Ohta, M., Okufuji, T., Matsushima, Y., Ikeda, M. The Effect of Lifestyle Modification on Physical Fitness and Work Ability in Different Workstyles. J UOEH,26,4,411-421, 2004
   3. Sato Y, Nanri H, Ohta M, Kasai H, Ikeda M. Increase of human MTH1 and decrease of 8-hydroxydeoxyguanosine in leukocyte DNA by acute and chronic exercise in healthy male subjects. Biochem Biophys Res Commun. 2003 May 30;305(2):333-8.
   4. Sano H, Sata T, Nanri H, Ikeda M, Shigematsu A : Thioredoxin is associated with endotoxin tolerance in mice., Crit Care Med. ; 30(1) : 190-194, 2002
      Sato Y, Nanri H, Ohta M, Ito H, Nishioka K, Ikeda M : _gWaist Hip Circumference Ratio (WHR) Correlates with Lipid Peroxidation_h., J UOEH ; Vol.24, Suppl.2;122-129, 2002
   5. Ohta M, Nanri H, Okazaki T, Omae T, Ikeda M : The effect of lifestyle modification on oxidative stress in obese and non-obese subjects., J UOEH ; Vol.24, Suppl.2;99-105, 2002
   6. Ohta M, Nanri H, Sato Y, Okazaki T, Omae T, Ikeda M : Evaluation of effects of health promotion program through the use of questionnaires., J UOEH ; Vol.24, Suppl.2; 174-184, 2002
   7. Eguchi Y, Tsuru M, Nanri H, Ikeda M : Application of a two-dimensional classification of body composition in assessment of lifestyle modification in Obese Subjects., J UOEH ; Vol.24, Suppl.2; 110-115, 2002
   8. Himeno, E, Nishino, K, Nanri, H, Okazaki, T, Komatsu, T, Ikeda,M : Evaluation of the effects of exercise and a mild hypocaloric diet on cardiovascular factors in obese subjects, J. UOEH ; 23: 1-12, 2001.
   9. Okazaki T, Himeno E, Nanri H, Ikeda M : Effects of a Community-Based Lifestyle-Modification Program on Cardiovascular Risk Factors in Middle-Aged Women., Hypertension Research ; 24(6):647-653, 2001
   10. Shibata E, Ejima K, Nanri H, Toki N, Koyama C, Ikeda M, Kashimura M. : Enhanced Protein Levels of Protein thiol/ Disulphide Oxidoreductases in Placentae from Preeclamptic Subjects., Placenta ; 22(6):566-572, 2001
   11. Ejima K, Nanri H, Araki M, Koji T, Shibata E, Kashimura M, Ikeda M: Expression of mitochondrial thioredoxin-dependent antioxidant protein, SP-22, in normal human and inflammatory mouse placentas. Placenta, 21, 847-852, 2000
   12. Ejima K, Koji T, Tsuruta D, Nanri H, Kashimura M, Ikeda M: Induction of Apoptosis in Placenta of Pregnant Mice Exposed to Lipopolysaccharides : Possible Involvemnt of Fas/Fas Ligand System., Biology of Reproduction, 62, 178-185, 2000
   13. Harada Y, Ikeda M, Murasato Y, Suzuka H, Nanri H, Hayashida Y: Integrative Effects of Nitric Oxide and Endothelium-Derived Hyperpolarizing Factor Induced by Acetylcholine and Bradykinin in Rat Hindquarter Perfusion., Biology and Chemistry, 4, 354-362, 2000
   14. Okazaki T, Himeno E, Nanri H, Ogata H, Ikeda M: Effects of mild aerobic exercise and a mild hypocaloric diet on plasma leptin in sedentary women., Clin. Exp. Pharmacol Physiol, 26, 415-420, 1999
   15. Himeno E, Nishino K, Okazaki T, Nanri H, Ikeda M: A weight reduction and weight maintenance program with long-lasting improvement in left ventricular mass and blood pressure., Am. J. Hypertension , 12, 682-690, 1999
   16. Murasato Y, Harada Y, Ikeda M, Nakashima Y, Hayashida Y: Effect of magnesium deficiency on autonomic circulatory regulation in conscious rats., Hypertension, 34, 247-252, 1999
   17. Araki M, Nanri H, Ejima K, Murasato Y, Fujiwara T, Nakashima Y, Ikeda M: Antioxidant Function of the Mitochondrial Protein SP-22 in the Cardiovascular System., J. Biol. Chem., 274, 2271-2278, 1999
   18. Ejima K, Nanri H, Toki N, Kashimura M, Ikeda M: Localization of thioredoxin reductase and thioredoxin in normal human placenta and their protective effect against oxidative stress., Placenta, 20, 95-101, 1999
   19. Ejima K, Nanri H, Araki M, Uchida K, Kashimura M, Ikeda M: 17ƒÀ-estradiol induces protein thiol/disulfide oxidoreductases and protects cultured bovine aortic endothelial cells from oxidative stress, Eur. J Endocrinol, 140, 608-613, 1999
   20. Ikeda M, Nakamura T, Harada Y, Hayashida Y: Direct Evidence of the release of nitric oxide by ergonovine in the rat hindquarter perfusion system., The Biology of Nitric Oxide Part6, Portland Press,London, p135, 1998.
   21. Hayashida Y, Nakamura T, Harada Y, Ikeda M: Measurement of nitric oxide release by acetylcholine and bradykinin in hindquarter perfusion in the rat., The Biology of Nitric Oxide Part6, Portland Press,London, p288
       

1. Academic Activities
   Member of Jpn Society of Hypertension, Member of Jpn Society ofinternal Medicine,Member of Jpn Circulation Society, Member of Jpn Society of Endocrinology, Member of Jpn Society for Occupational Health , Jpn Society of Nutrition and Dietetics

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