University of Occupational and Environmental Health,
1-1, Iseigaoka, Yahatanishi-ku, Kitakyushu-shi, 807-8555, Japan
The Radioisotope Research Center, which is one of the most
important facilities for the development of medical and life sciences,
is used for a variety of experiments by the faculty, and conducts
training classes in safe handling of radiations and radioisotopes
for the students and the new members of the faculty.
Its facilities are able to accommodate various types of experiments. This
center is equipped with separate laboratories where students and staff
members can conduct experiments safely with various types of radioisotopes.
Subjects for study
The following studies have been made in Radioisotope Research
- Health effects of low-level radiation.
- Biological assessment of exposure to tritium beta rays.
- Transcription regulation of cytokine genes in hematopoietic
- The mechanisms of adhesion molecules in immune system and
inflammation, in the contexts with cytokines and proteoglycans.
- Characterization of molecular mechanisms of hormone resistance
disorders in endocrine diseases.
- The pathogenesis and regulation of collagen-induced arthritis.
- The role of superantigen in the pathogenesis of autoimmune
- Studies on biological role of metallothionein in immune response.
- Peptide leukotrienes such as LTC4, LTD4 and LTE4 were assayed
in the samples of blood and tourniquet muscle at the tourniquet
- Taxonomic study on marine bacteria.
- Biosynthesis of archaebacterial lipids.
- Estimation of telomerase activity with modified TRAP assay
in oral cancer tissues.
- Alterations of expression of the cytoskeleton after immortalization
of human fibroblasts.
- Molecular biological research on occupational lung disease.
- Regulation of mucin gene expression.
- Expression of the immediate early genes in the nervous system.
- Alterations of carnitine concentrations in the brain.
- Effects of neurotoxins on activities of membrane-bound enzymes.
- Remodeling of the artery after birth.
- Regulation of histamine-receptors in the artery.
- Mechanism for invasion and metastasis of human esophageal
- Regulation of catecholamine synthesis and secretion by protein
- Interactions among the nervous, endocrine and immune systems.
- Molecular and biochemical analysis of ion channels and receptors.
- Structure-function relationship of the sodium pump.
- Sex hormone receptors in gastroenterological cancers.
- Invasion and metastasis of cancer cells.
- Fuzzy-set cloning for functional protein targeting and application
to investigation of histo-reguratory proteins.
- Charactarization of active profilin and woundhealin during
- Gene expression of AVP in lithium induced diabetes insipidns.
- Signal transduction of vasoactive peptides in renal preparations.
- Anti mitogenetic effect of vasoactiv peptides in rat renal
- 2-Hydroxyadenine as oxidative DNA damage: its formation and
- Formation of 8-hydroxyguanine in DNA by aging and oxidative
- Increased 8-hydroxyguanine level in DNA and repair activity
in rat kidney after administration of a renal carcinogen, ferric
- Increase of type of oxidative DNA damage, 8-hydroxyguanine
and its repair activity in human leukocytes by cigarette smoking.
- Analyses of [35S]methionine-labeled peptides released from
Weibel-Palade bodies of endothelial cells by two-dimensional
polyacrylamide gel electrophoresis.
- The response of mechanically compressed cultured astrocytes.
- Analysis of the expression of heat shock protein gone in
response to a variety of stresses and the regulation of its promoter
- Regulation of transcription of nuclear hormone receptor genes
in neural cells.
- Identification of target genes of nuclear hormone receptors.
- Analysis of regulation mechanism on gene expression by in
- Measurement of telomerase activity: correlation between cancer
and telomerase activity.
- The regulation of gene expression in the neuroendorine and
immune system .
- The role of cardiovascular-related peptides and cytokines
in neuroendocrine and immune system.
- In vitro expression of sea urchin (Hemicentrotus pulcherrimus)
G-string binding protein.
- Sequence specific DNA binding assay of G-string binding protein
using DNA affinity column.
- Effect of sleep, circadian rhythm, and shift work on allergic
- Role of anterior hypothalamus on allergic respiratory reaction.
- Stress and coping.
- edited by Radioisotope Research Center
- Last Update: Aug.16 2005