2017

論文

Oyabu T, Myojo T, Byeong-Woo Lee BW, Okada T, Izumi H, Yoshiura Y, Tomonaga T, Li
YS, Kawai K, Shimada M, Kubo M, Yamamoto K, Kawaguchi K, Sasaki T, Morimoto Y:
Biopersistence of NiO and TiO2 Nanoparticles Following Intratracheal Instillation
and Inhalation, Int. J. Mol. Sci. 2017, 18, 2757 doi:10.3390/ijms18122757

2016

論文

Okada T, Ogami A, Lee BW, Kadoya C, Oyabu T, Myojo T: Pulmonary responses in rat lungs
after intratracheal instillation of 4 crystal forms of titanium dioxide
nanoparticles, J Occup Health 58:602-611, 2016.

Shinohara N, Nakazato T, Ohkawa K, Tamura M, Kobayashi N, Morimoto Y, Oyabu T, Myojo T,
Shimada M, Yamamoto K, Tao H, Ema M, Naya M, Nakanishi J: Long-term retention of pristine multi-walled carbon nanotubes in rat lungs after intratracheal instillation, J Appl Toxicol 36:501-9, 2016.

Oyabu T, Morimoto Y, Izumi H, Yoshiura Y, Tomonaga T, Lee B, Okada T, Myojo T,
Shimada M, Kubo M, Yamamoto K, Kawaguchi K, Sasaki T: Comparison between whole-body
inhalation and nose-only inhalation on the deposition and health effects of
nanoparticles, Environ Health and Prev Med, 21(1) 42-48, 2016.

2015

論文

Nakanishi J, Morimoto Y, Ogura I, Kobayashi N, Naya M, Ema M, Endoh S, Shimada M, Ogami A, Myojo T,
Oyabu T, Gamo M, Kishimoto A, Igarashi T, Hanai S:
 Assessment of the Carbon Nanotube Group
Risk Analysis,35(10):1940-1956 　

Kadoya C, Lee BW, Ogami A, Oyabu T, Nishi K, Yamamoto M, Todoroki M, Morimoto Y, Tanaka I, Myojo T
 Analysis of pulmonary surfactant in rat lungs after inhalation of nanomaterials: Fullerenes, nickel oxide and multi-walled carbon nanotubes.
Nanotoxicology, DOI: 10.3109/17435390.2015.1039093

Oyabu T, Morimoto Y, Izumi H, Yoshiura Y, Tomonaga T, Lee BW, Okada T, Myojo T, Shimada M, Kubo M, Yamamoto K, Kawaguchi K, Sasaki T.
 Comparison between whole-body inhalation and nose-only inhalation on the deposition and health effects of nanoparticles.
Environ Health Prev Med. DOI 10.1007/s12199-015-0493-z:　

2013

論文

Mizuguchi Y, Myojo T, Oyabu T, Hashiba M, Lee BW, Yamamoto M, Todoroki M, Nishi K, Kadoya C, Ogami A, Morimoto Y, Tanaka I, Shimada M, Uchida K, Endoh S, Nakanishi J.:
Comparison of dose-response relations between 4-week inhalation and intratracheal instillation of NiO nanoparticles using polimorphonuclear neutrophils in bronchoalveolar lavage fluid as a biomarker of pulmonary inflammation.
Inhalation Toxicology, 25(1): 29-36
　

Oyabu T, Morimoto Y, Hirohashi M, Horie M, Kambara T, Lee BW, Hashiba M, Mizuguchi Y, Myojo T, Kuroda E.:
Dose-dependent pulmonary response of well-dispersed titanium dioxide nanoparticles following intratracheal instillation.
J Nanopart Res (2013) 15:1600 DOI 10.1007/s11051-013-1600-y
　

2012

論文

Kadoya C, Ogami A, Morimoto Y, Myojo T, Oyabu T, Nishi K, Yamamoto M, Todoroki M, Tanaka I.:
Analysis of Bronchoalveolar　Lavage Fluid Adhering to Lung Surfactant.
Industrial Health　50(1):31 – 36

2011

論文

Yamamoto, M ・Oyabu, T.・Morimoto, Y.・Ogami, A.・Kadoya, C.・Nishi, K.・Todoroki,
M.・Myojo, T.・Tanaka, I.:
Biopersistence of potassium hexatitanate in inhalation and intratracheal
instillation studies.
Inhalation Toxicology　23(1-4):196 - 204
　

Myojo T, Oyabu T, Ogami A, Hirohashi M, Murakami M, Yamamoto M, Kadoya C, Nishi K, Yamasaki S, Morimoto Y, Tanaka I, Shimada M, Endoh S.:
Monitoring of C60 aerosol concentrations during 4-week inhalation study using a carbon aerosol analyzer with adjusted analytical protocol.
J Nanopart Res　13 :2063 - 2071
　

明星 敏彦, 大藪 貴子, 大神 明, 森本 泰夫, 西 賢一郎, 角谷 力, 山本 誠, 轟木 基, 水口 要平, 李 秉雨, 橋場 昌義, 神原 辰徳:
防じんマスクのナノ粒子に対する捕集性能
Journal of UOEH　33(2):163 - 171
　

Oyabu T, Myojo T, Morimoto Y, Ogami A, Hirohashi M, Yamamoto M, Todoroki M, Mizuguchi Y, Hashiba M, Lee B, Shimada M, Wang W-N, Uchida K, Endoh S, Kobayashi N. Yamamoto K, Fujita K, Mizuno K, Inada M, Tanaka I.:
Biopersisitence of inhaled MWCNT in rat lungs in a 4-week well- characterized exposure
Inhalation Toxicology　23(12-1):784 - 791
　

2010

著書

明星 敏彦,森本 泰夫,大神 明,大藪 貴子,田中 勇武:
ナノリスクとナノ粒子, 粉体技術が挑む究極のエネルギーと環境調和
日刊工業新聞社 pp 98 - 105
　

明星 敏彦,大藪 貴子,大神 明,森本 泰夫:
第６章　ナノ粒子・ナノ物質の安全な利用
粉体工学会誌 47(7):485-489
　

論文

Myojo T, Ogami A, Oyabu T, Morimoto Y, Hirohashi M, Murakami M, Nishi K, Kadoya C, Tanaka I.:
Risk assessment of airborne fine particles and nanoparticles
Advanced Powder Technology　21(5):507 - 512

2009

著書

明星敏彦、大藪貴子、田中勇武：
工業用ナノマテリアルの曝露に対するリスク低減対策
エアロゾル研究　日本エアロゾル学会　32-36（2009）

Ogami A, Morimoto Y, Murakami M, Myojo T, Oyabu T, Tanaka I:
(Proceedings) Biological effects of nano-nickel in rat lungs after administration by inhalation and by intratracheal instillation
Journal of Physics 1-5 (2009)

論文

森本泰夫、大藪貴子、笠井孝彦、田中勇武：
吸入物質の肺内動態と障害
日本胸部臨床　68():supple:23-31 (2009)

Myojo T, Oyabu T, Nishi K, Kadoya C, Tanaka I, Ono-Ogasawara M, Sakae H, Shirai T:
Aerosol generation and measurement of multi-wall carbon nanotubes
Jourmal of Nanoparticle Research 11(1):91-99 (2009)

Shimada M, Wang W-N, Okuyama K, Myojo T, Oyabu T, Morimoto Y, Tanaka I, Endo S, Uchida K, Ehara K, Sakurai H, Yamamoto K, Nakanishi J:
Development and Evaluation of an Aerosol Generation and Supplying System for Inhalation Experiments of Manufactured Nanoparticles
ENVIRONMENTAL SCIENCE & TECHNOLOGY　43(14)::5529-5534 (2009)

Ogami A, Morimoto Y, Myojo T, Oyabu T, Murakami M, Todoroki M, Nishi K, Kadoya C, Yamamoto M, Tanaka I:
Pathological features of different sizes of nickel oxide following intratracheal instillation in rats
Inhalation Toxicology ():iFirst:1-7 (2009)

Morimoto Y, Hirohashi M, kasai T, Oyabu T, Ogami A, Myojo T, Murakami M, Nishi K, Kadoya C, Todoroki Motoi, Yamamoto M, Kawai K, Kasai H, Tanaka I:
Effect of polymerized toner on rat lung in chronic inhalation study.
Inhalation Toxicology　21(11)::898-905 (2009)

Nishi K, Morimoto Y, Ogami A, Murakami M, Myojo T, Oyabu T, Kadoya C, Yamamoto M, Todoroki Motoi, Hirohashi M, Yamasaki S, Fujita K, Endo S, Uchida K, Yamamoto K, Nakanishi J, Tanaka I:
Expression of cytokine-induced neutrophil chemoattractant in rat lungs by intratracheal instillation of nickel oxide nanoparticles
Inhalation Toxicology　21(12)::1030-1039 (2009)

2008

著書

明星敏彦、大藪貴子、田中勇武：
２１世紀の吸入療法　第４章　吸入療法に係わる諸問題
�X仙台気道研究所：82-89

明星敏彦、大藪貴子、田中勇武：
ナノ粒子のリスクアセスメントについて
日本労働衛生工学会：23-28

明星敏彦、大藪貴子、田中勇武：
作業環境中のナノ粒子の評価の動向
（社）日本空気清浄協会：36-41

森本泰夫、廣橋雅美、矢寺和博、大藪貴子、大神　明、明星敏彦、村上昌宏、田中勇武：
(Proceedings) (シンポジウム) 石綿を含む職業性肺疾患における電子顕微鏡検査の有用性
J. Electr. Microsc. Technol. Med. Biol. 22(2)
医学生物学電子顕微鏡技術学会 97-98（2008）

論文

Oyabu T, Ogami A, Morimoto Y, Myojo T, Murakami M, Yamato H, Tanaka I:
Simple Flow-through Solubility Measurement Apparatus and its Effectiveness for Hazard Assessment of Particles/Fibers
Journal of Occupational Health 50(3):279-282

森本泰夫、大神　明、大藪貴子、村上昌宏、明星敏彦、廣橋雅美、山崎小由美、西賢一郎、角谷　力、轟木　基、山本　誠、田中勇武：
金属ナノ粒子の吸入曝露試験による肺傷害の検討
分子呼吸器病 12(1):65-70

Kido T, Morimoto Y, Asonum E, Yatera K, Ogami A, Oyabu T, Tanaka I, Kido, M:
Chrysotile Asbestos Causes AEC Apoptosis via the Caspase Activation In Vitro and In Vivo.
Inhalation Toxicology 20(3):339-347

2007

著書

明星敏彦、大藪貴子、田中勇武：
第３節　ナノ粒子の評価と環境衛生・ナノカーボンハンドブック
エヌ・ティー・エス 866-874

明星敏彦、大藪貴子、田中勇武：
ナノ粒子のリスクアセスメント
財団法人ビル管理教育センター：40-45

論文

Oyabu T, Ogami A, Morimoto Y, Shimada M, Lenggoro W, Okuyama K, Tanaka I:
Biopersistence of Inhaled Nickel Oxide Nanoparticles in Rat Lung
Inhalation Toxicology 19(S):55−58

Akiyama I, Ogami A, Oyabu T, Yamato H, Morimoto Y, Tanaka I:
Pulmonary Effects and Biopersistence of Deposited Silicon Carbide Whisker After 1-Year
Inhalation in Rats　Inhalation Toxicology 19(2):141-147

Morimoto Y, Ogami A, Nagatomo H, Hirohashi M, Oyabu T, Kuroda K, Kawanami Y, Murakami M, Myojo T, Higashi T, Tanaka I:
Calcitonin Gene-Related Peptide (CGRP) as Hazard-Marker for Lung Injury Induced by Dusts.
Inhalation Toxicology 19(3):283-289

Kajiwara T, Ogami A, Yamato H, Oyabu T, Morimoto Y, Tanaka I:
Effect of Particle Size of Intratracheally Instilled Crystalline Silica on Pulmonary　inflammation
Journal of Occupational Health 49(2):88−94

Nagatomo H, Morimoto Y, Ogami A, Hirohashi M, Oyabu T, Kuroda K, Higashi T, Tanaka I:
Change of Heme Oxygenase-1 Expression in Lung Injury Induced by Chrysotile Asbestos In Vivo and In Vitro.
Inhalation Toxicology 19(4):317-323

Kim H, Morimoto Y, Ogami A, Nagatomo H, Hirohashi M, Oyabu T, Kawanami Y, Kuroda E, Higashi T, Tanaka I:
Differential Expression of EC-SOD, Mn-SOD and CuZn-SOD in Rat Lung Exposed to Crystalline Silica.　
Journal of Occupational Health 49(3):242-248

Myojo T, Oyabu T, Kadoya C, Nishi K, Tanaka I:
Redesign of a Static Horizontal Elutriator to Perform According to the ISO 7708 Respirable Convention
The Annals of Occupational Hygiene 51(4):371-378

Ogami A, Morimoto Y, Myojo T, Oyabu T, Murakami M, Nishi K, Kadoya C, Tanaka I:
Histopathological Changes in Rat Lung Following Intratracheal Instillation of Silicon Carbide Whiskers and Potassium Octatitanate Whiskers.
Inhalation Toxicology 19(9):753-758

明星敏彦、大神　明、大藪貴子、森本泰夫、廣橋雅美、村上昌宏、西賢一郎、角谷　力、田中勇武：
微小粒子（ナノ粒子）のリスクアセスメント
粉体工学会誌 44(8):587-592

2006

著書

Yamato H, Ogami A, Nagafuchi Y, Oyabu T, Tanaka I:
Tobacco Control in Workplace and Its Effect on Reducing Smoking Prevalence
The 25th UOEH International Symposium “COMFOT in the Workplace 159-164

論文

Oyabu T, Yamato H, Ogami A, Morimoto Y, Akiyama I, Ishimatsu S, Hori H, Tanaka I:
The Effect of Lung Burden on Biopersistence and Pulmonary Effects in Rats Exposed to　Potassium Octatitanate Whiskers by Intratracheal Instillation
Journal of Occupational Health 48(1):44−48

Nagatomo H, Morimoto Y, Oyabu T, Hirohashi M, Ogami A, Yamato H, Kuroda K, Higashi T, Tanaka I:
Expression of Heme Oxygenase-1 in the Lungs of Rats Exposed to Crystalline Silica
Journal of Occupational Health 48(2):124-128

Kuroda K, Morimoto Y, Ogami A, Oyabu T, Nagatomo H, Hirohashi M, Yamato H, Nagafuchi Y, Tanaka I:
Phospholipid Concentration in Lung Lavage Fluid as Biomarker for Pulmonary Fibrosis
Inhalation Toxicology 18(5):389−393

大神　明、村上昌宏、大藪貴子、森本泰夫、田中勇武：
ナノトキシコロジーの概念
産業医学ジャーナル　29(4)113-117

大神　明、森本泰夫、村上昌宏、大藪貴子、明星敏彦、黒田香織、廣橋雅美、西賢一郎、角谷　力、田中勇武：
【最近のトピックス】微細粒子の肺への影響の動向
空気清浄 44(4):230-239

2005

論文

Morimoto Y, Kim,H-N, Oyabu T, Hirohashi M, Nagatomo H, Ogami A, Yamato H, Higashi T, Tanaka I, Kasai T:
Effect of long-term inhalation of toner on extracellular matrix in the lungs of rats in vivo　Inhalation Toxicology 17(3):153−159

Nagatomo H, Morimoto Y, Oyabu T, Hirohashi M, Ogami A, Yamato H, Kuroda K, Higashi T, Tanaka I:
Expression of heme oxygenase-1 in the lungs of rats exposed to crocidolite asbestos.
Inhalation Toxicology 17(6):293−296

大神　明、大和　浩、永渕祥大、大藪貴子、田中勇武：
「職場における喫煙対策のためのガイドライン」に準処した喫煙室の設置とリアルタイムモニタリングによる粉じん濃度の測定
作業環境 26(3):48−53

Morimoto Y, Kim,H-N, Oyabu T, Hirohashi M, Nagatomo H, Ogami A, Yamato H, Obata Y, Kasai H, Higashi T, Tanaka I:
Negative effect of long-term inhalation of toner on formation of 8-hydroxydeoxyguanosine in DNA in the lungs of rats in vivo.
Inhalation Toxicology 17(13):749−753

Morimoto Y, Nagatomo H, Hirohashi M, Oyabu T, Ogami A, Yamato H, Kuroda K, Obata Y, Higashi T, Tanaka I:
Expression of Clara Cell Secretory Protein in the Lungs of Rats Exposed to Crystalline Silica In Vivo
Journal of Occupational Health 47(6)504-509

2004

著書

森本泰夫、笠井孝彦、大藪貴子、田中勇武：
第４節 気管と肺・第４項 じん肺モデル
モデル動物の作成と維持、森脇和郎　他編、エル・アイ・シー 325-333

論文

大和　浩、秋山　泉、大神　明、梶原隆芳、黒田香織、大藪貴子、森本泰夫、保利　一、田中勇武：
有効な喫煙室の設置手法と粉じん濃度のリアルタイムモニタリングの有用性について
産衛誌、46(2):55−60

大和　浩、大神　明、大藪貴子、田中勇武：
職場の受動喫煙対策
日本呼吸器学会雑誌、42(7):616−619

Ogami,A. Morimoto,Y. Yamato,H. Oyabu,T. Kajiwara,Y. Tanaka,I. :
Patterns of Histopathological Change Determined by the Point Counting Method and Its Application for the Hazard Assessment of Respirable Dust
Inhalation Toxicology,16:793−800

Oyabu,T. Yamato,H. Ogami,A. Morimoto,Y. Akiyama,I. Ishimatsu,S. Hori,H. Tanaka,I. :
The Effect of Lung Burden on Biopersistence and Pulmonary Effects in Rats Exposed to Potassium Octatitanate　Whiskers by Inhalation
J Occup Health,46:382−390

Morimoto,Y. Oyabu,T. Yamato,H. Hirohashi,M. Ogami,A. Nagatomo,H. Kuroda,K. Higashi,T. Tanaka,I. :
Biopersistence of Japanese Glasswool Fibers in Short-term Biopersistence Test by Intracheal Instillation
Journal of Aerosol Research,19(3):207−210

2003

論文

Ishimatsu,S. Hori,H. Oyabu,T. Tanaka,I.:
Biopersistence of graphite whiskers deposited in rat lungs by 4-week inhalation
Inhalation Toxicology,15:53−66

Akiyama,I. Ogami,A. Oyabu,T. Yamato,H. Morimoto,Y. Tanaka,I. :
Clearance of Deposited Silicon Carbide Whisker from Rat Lungs Inhaled during a 4-Week Exposure
Journal of Occupational Health,45(1):31−35

Yamato,H. Oyabu,T. Ogami,A. Morimoto,Y. Higashi,T. Tanaka,I. :
Pulmonary Effects and Clearance After Long-Term Inhalation of Potassium Octatitanate Whiskers in Rats
Inhalation Toxicology,15(14):1421−1434

Morimoto,Y. Ding,L. Oyabu,T. Hirohashi,M. Kim,H-N. Ogami,A. Yamato,H. Akiyama,I. Hori,H. Higashi,T. Tanaka,I. :
Expression of Clara Cell Secretory Protein in the Lungs of Rats Exposed to Silicon-carbide whisker in vivo .
Toxicology letter,145(3):273−279

Morimoto,Y. Ding,L. Oyabu,T. Hirohashi,M. Kim,H-N. Ogami,A. Yamato,H. Akiyama,I. Hori,H. Higashi,T. Tanaka,I. :
Gene Expression of Surfactant Protein-A and Thyroid Transcription Factor-1 in Lungs of Rats Exposed to Silicon-Carbide Whisker in vivo
J Occpational Health,45:307−312

2002

論文

保利　一、百道敏久、大藪貴子、石松維世、大和　浩、田中勇武：
臭化メチルガスのマウスおよびラットに対する急性生体影響
産業医科大学雑誌24(1):71−75

Yamato,H. Morimoto,Y. Tsuda,T. Ogami,A. Oyabu,T. Ishimatsu,S. Hori,H. Tanaka,I. :
Clearance of Inhaled Potassium Octatitanate Whisker from Rat Lungs
Journal of Occupational Health,44:39-34

Ogami,A. Yamato,H. Oyabu,T. Morimoto,Y. Akiyama,I. Kajiwara,T. Hyakudo,T. Tanaka,I. :
Assessment of Exposure to ETS in a Workplace - Measurement by Real-Time Monitering of Paticulate Matter -
Journal of UOEH,24:46-51

Yamato,H. Ogami,A. Oyabu,T. Morimoto,Y. Tanaka,I. Nakamura,M. Oshima,A. :
A Successful Smoking Control in Workplaces
Joumal of UOEH,24:91-98

Hori,H. Hyakudo,T. Oyabu,T. Ishimatsu,S. Yamato,H. Tanaka,I. :
Effects of inhaled methyl bromide gas on the metabolic system and kinetics of bromine ion concentration
J UOEH,24(2):171−180

Ogami,A. Morimoto,Y. Yamato,H. Oyabu,T. Akiyama,I. Kajiwara,T. Ominami,S. Tanaka,I. :
Effect of Crystalline Silica Particles on PMN Release from the Bone Marrow
Annals of Occupational Hygiene,46(1):43−49

Morimoto,Y. Ding,L. Kim,H-N. Hirohashi,M. Yamato,H. Ogami,A. Oyabu,T. Kajiwara,T. Hyakudo,T. Hori,H. Higashi,T. Tanaka,I. :
Combined effect of cigarette smoke (side stream) and mineral fibers on the gene expression of cytokines mRNA in rat lungs
Journal of UOEH,24(sup):32−37

2001

著書

Tanaka, I. Yamato,H. Oyabu,T. Ogami,A. :
Biopersistence of Man-Made Fibers by Animal Inhalation Experments in Recent Reports
Industrial Health 114−118

論文

大藪貴子、森本泰夫、田中勇武：
シリカ粒子の肺障害関連因子 〜肺内滞留粒子量〜
エアロゾル研究、16(4):275-279

Tanaka,I. Yamato,H. Oyabu,T. Ogami,A. :
Biopersistence of Man-Made Fibers by Animal Inhalation Experiments inRecent Reports
Industrial Health,39(2)114-118

Ogami,A. Morimoto,Y. Yamato,H. Oyabu,T. Akiyama,I. Tanaka,I. :
Short Term Effect of Silicon Carbide Whisker to the Rat Lung
Industrial Health,39(2)175-182

Morimoto,Y. Tsuda,T. Yamato,H. Oyabu,T. Higashi,T. Tanaka,I. Kasai,T. Ishimatsu,S. Hori,H. Kido,M. :
Comparison of gene expression of cytokines mRNA in lungs of rats induced by intratracheal instillation and inhalation of mineral fibers
Inhalation Toxicology,13:589-601

Ding,L. Morimoto,Y. Oyabu,T. Kim,HN. Ogami,A. Yatera,K. Hirohashi,M. Yamato,H. Hori,H. Higashi,T. Tanaka,I. :
Gene Expression of Clara Cell Secretory Protein, Surfactant Protein-A and Thyroid Transcription Factor-1 in the Lungs of Rats Exposed to Potassium Octatitanate Whiskers in vivo
Journal of Occupational Health,44(3):111-117

2000

著書

大藪貴子、東　敏昭、田中勇武：
第一章　環境たばこ煙、喫煙の科学−職場の分煙テキストブック
産業医科大学産業生態科学研究所
労働調査会、東京8−18

論文

大和浩、秋山泉、溝上哲也、大神明、大藪貴子、森本泰夫、保利一、田中勇武：
事務室における空間分煙の３事例
労働衛生コンサルタント、22(54):42-49

Ishidao,T. Hori,H. Oyabu,T. Yamato,H. Morimoto,Y. Tanaka,I. :
Effect of simultaneous exposure to bicomponent organic vapors on their metabolism in rats
Journal of UOEH, 22:250-254