Research Associate
  1. Takeshi Hirano (MD, Ph.D.)

  2. Key words
    Oncology / DNA repair / Gastroenterology

  3. Recent Selected Publications
    Hirano, T., Homma, Y., Kasai, H. Formation of 8-hydroxyguanine in DNA by aging and oxidative stress. In "Oxidative Stress and Aging", Bilkhauser Verlag/Basel, pp69-76(1995)

    Hirano, T., Yamaguchi, Y., Hirano, H., and Kasai, H. Age-associated change of 8-hydroxyguanine repair activity in cultured human fibroblasts. Biochem. Biophys. Res. Commun.,214, 1157-1162 (1995)

    Abe, T., Konishi, T., Hirano, T., Kasai, H., Shimizu, K., Kashimura, M., and Higashi, K. Possible correlation between DNA damage induced by hydrogen peroxide and translocation of heat shock 70 protein into the nucleus. Biochem. Biophys. Res. Commun., 206, 548-555 (1995)

    Yamaguchi, R., Hirano, T., Asami, S., Sugita, A., and Kasai, H. Increase in the 8-hydroxyguanine repair activity in the rat kidney after the administration of a renal carcinogen, ferric nitrilotriacetate. Environmental Health Perspective, 104, 651-653 (1996)

    Asami, S., Hirano, T., Yamaguchi, R., Tomioka, Y., Itoh, H., and Kasai, H. Increase of a type of oxidative DNA damage, 8-hydroxyguanine, and its repair activity in human leukocytes by cigarette smoking. Cancer Res., 56, 2546-2549 (1996)

    Hirano, T., Yamaguchi, R., Asami, S., Iwamoto, N. and Kasai, H. 8-Hydroxyguanine levels in nuclear DNA and its repair activity in rat organs associated with age. J. Gerontol., 51A, 303-307(1996)

  4. Membership in academic society
    Japanese Cancer Association, The Molecular Biology Society of Japan, The Japanese Biochemical Society, The Japanese Society of Gastroenterology, The Japanese Society of Hepatology, The Japanese Society of Internal Medicine, Japan Gastroenterological Endoscopy Society, Japan Society for Occupational Health, UOEH Asociation of Health Sciences
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