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Toyohi Isse, M.D, Ph.D.
Curriculum Vitae
Recent Publications
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Toyohi ISSE, M.D., Ph.D.
Associate Professor, Career Guidance Department
Mailing address:
Iseigaoka 1-1, Yahatansihi
Kitakyushu, Fukuoka 807-8555
JAPAN
Telephone:
Office: 81-(0)93-691-7294
Fax: 81-(0)93-603-6444
Affiliations:
Member, University of Occupational and Environmental Health
Training and Education:
Ph.D., Department of Physiology, University
of Occupational and Environmental
Health, School of Medicine.
Clinical/Research interest:
1. Genetic factors involved in the
alcohol drinking preference and toxicity. Individual differences in alcohol
preference are clearly genetically determined, which may translate into a
genetic predisposition for alcohol abuse and alcoholism. Specific genes
responsible for the increased or decreased susceptibility to alcohol abuse
remain largely unknown. Our laboratory studies the role of aldehyde
dehydrogenase 2 (ALDH2), as genetic factors associated with
alcoholism--including toxicity, carcinogenesis, abuse, and drinking
preference. Experimental approaches include transgenic mouse lines.
2. Gene expression approach of finding new biomarkers.
Using micro array and quantitative RT-PCR techniques.
3. Chemical-protein adducts and chemical metabolite
analysis.
Teaching:
Professional Program:
Hygiene, Occupational Health
Graduate Program:
Toxicology, Biomarker, Molecular Biology
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