産業医科大学分子標的治療内科学特別講座は、膠原病リウマチ性疾患のよりよい治療の確立を目指しています

産業医科大学医学部 分子標的治療内科学特別講座

TEL. 093-603-1611

〒807-8555 福岡県北九州市八幡西区医生ケ丘1番1号

業績集

スタッフ別の受賞歴と論文です。

田中 良哉

受賞歴

論文等（令和7年1月現在）

区分 邦文 欧文
著書 419編 14編
総説 953編 152編
原著 51編 749編
症例報告 176編 122編
合計 1,599編 1,037編

宮川 一平

受賞歴

論文

  1. Iwata S, Saito K, Tokunaga M, Yamaoka K, Nawata M, Yukawa S, Hanami K, Fukuyo S, Miyagawa I, Kubo S, Tanaka Y. Phenotypic changes of lymphocytes in patients with systemic lupus erythematosus who are in longterm remission after B cell depletion therapy with rituximab. J Rheumatol; 2011; 4:633-41

  2. Tanaka Y, Yamanaka H, Saito K, Iwata S, Miyagawa I, Seto Y, Momohara S, Nagasawa H, Kameda H, Kaneko Y, Izumi K, Amano K, Takeuchi T. Structural damage disturb functional improvement in patients with rheumatoid arthritis treated with etanercept. Mod Rheumatol. 2012; 22:186-94.

  3. Yukawa S, Yamaoka K, Sawamukai N, Shimajiri S, Kubo S, Miyagawa I, Sonomoto K, Saito K, Tanaka Y. Dermal mast cell density in fingers reflects severity of skin sclerosis in systemic sclerosis. Mod Rheumatol. 2013; 23:1151-7

  4. Miyagawa I, Nakayamada S, Saito K, Hanami K, Nawata M, Sawamukai N, Nakano K, Yamaoka K, Tanaka Y. Study on the safety and efficacy of tocilizumab, an anti-IL-6 receptor antibody, in patients with rheumatoid arthritis complicated with AA amyloidosis. Mod Rheumatol. 2014; 24:405-9

  5. Zhang X, Yamaoka K, Sonomoto K, Kaneko H, Satake M, Yamamoto Y, Kondo M, Zhao J, Miyagawa I, Yamagata K, Fukuyo S, Okada Y, Tanaka Y. Local delivery of mesenchymal stem cells with poly-lactic-co-glycolic acid nano-fiber scaffold suppress arthritis in rats. PLoS One. 2014; 9: e114621.

  6. Kubo S, Nakayamada S, Nakano K, Hirata S, Fukuyo S, Miyagawa I, Hanami K, Saito K, Tanaka Y. Comparison of the efficacies of abatacept and tocilizumab in patients with rheumatoid arthritis by propensity score matching. Ann Rheum Dis. 2016:7;1321-7

  7. Yoshinari H, Saito K, Nakano K, Fukuyo S, Miyagawa I, Tanaka Y. A case of rheumatoid arthritis treated with infliximab who developed disseminated Penicillium marneffei infection after visit to Thailand. Modern Rheumatology Case Reports 2017

  8. Ishikawa Y, Miyagawa I, Nakano K, Satoh Y, Todoroki Y, Kubo S, Nawata A, Nakayamada S, Saito K, Tanaka Y. The occurrence of hypertrophic pachymeningitis with infiltration of IgG4-positive plasma cells and with different aetiology: report of three cases. Modern Rheumatology Case Reports 2017

  9. Miyagawa I, Nakayamada S, Nakano K, Yamagata K, Sakata K, Yamaoka K, Tanaka Y. Induction of Regulatory T Cells and Its Regulation with Insulin-like Growth Factor/Insulin-like Growth Factor Binding Protein-4 by Human Mesenchymal Stem Cells. J Immunol. 2017.199; 1616-1625

  10. Nakayamada S, Kubo S, Yoshikawa M, Miyazaki Y, Yunoue N, Iwata S, Miyagawa I, Hirata S, Nakano K, Saito K, Tanaka Y. Differential effects of biological DMARDs on peripheral immune cell phenotypes in patients with rheumatoid arthritis. Rheumatology (Oxford) 2018;1;57:164-174. DOI: 10.1093/rheumatology/kex012.

  11. Kubo S, Nakayamada S, Yoshikawa M, Miyazaki Y, Sakata K, Nakano K, Hanami K, Iwata S, Miyagawa I, Saito K, Tanaka Y. Peripheral Immunophenotyping Identifies Three Subgroups Based on T Cell Heterogeneity in Lupus Patients. Arthritis Rheumatol. 2017.69; 2029-2037

  12. Ohkubo N, Nakano K, Miyagawa I, Iwata S, Fukuyo S, Kubo S, Tamaki Y, Nakayamada S, Tanaka Y. Successful treatment with etanercept in a case of seronegative rheumatoid arthritis with corticosteroid/methotrexate-resistant pemphigus erythematosus. Modern Rheumatology Case Reports 2018.

  13. Nagayasu A, Kubo S, Nakano K, Nakayamada S, Iwata S, Miyagawa I, Fukuyo S, Saito K, Tanaka Y. IgG4-related Pleuritis with Elevated Adenosine Deaminase in Pleural Effusion: A Case Report. ntern Med. 2018;57:2251-2257. doi: 10.2169/internalmedicine.0387-17.

  14. Iwata S, Saito K, Hirata S, Ohkubo N, Nakayamada S, Nakano K, Hanami K, Kubo S, Miyagawa I, Yoshikawa M, Miyazaki Y, Yoshinari H, Tanaka Y. Efficacy and safety of anti-CD20 antibody rituximab for patients with refractory systemic lupus erythematosus. Lupus 2018;27:802-811. Doi: 0.1177/0961203317749047.

  15. Satoh Y, Nakano K, Yoshinari H, Nakayamada S, Iwata S, Kubo S, Miyagawa I, Yoshikawa M, Miyazaki Y, Saito K, Tanaka Y. A case of refractory lupus nephritis complicated by psoriasis vulgaris that was controlled with secukinumab. Lupus 2018;27:1202-1206. Doi: 10.1177/0961203318762598.

  16. Miyagawa I, Nakayamada S, Nakano K, Kubo S, Iwata S, Miyazaki Y, Yoshikawa M, Yoshinari H, Tanaka Y. Precision medicine using different biological DMARDs based on characteristic phenotypes of peripheral T helper cells in psoriatic arthritis. Rheumatology (Oxford) 2019:1;58:336-344. Doi: 10.1093/rheumatology/key069.

  17. Kubo S, Todoroki Y, Nakayamada S, Nakano K, Satoh M, Nawata A, Satoh Y, Miyagawa I, Saito K, V Smith, M Cutolo, Tanaka Y. Significance of nailfold videocapillaroscopy in patients with idiopathic inflammatory myopathies. Rheumatology (Oxford) 2019.1;58:120-130. DOI: 10.1093/rheumatology/key257.

  18. Miyagawa I, Nakano K, Nakayamada S, Iwata S, Hanami K, Fukuyo S, Kubo S, Inoue Y, Ueno M, Tanaka Y. The effectiveness and safety of hydroxychloroquine therapy with or without corticosteroid in patients with systemic lupus erythematosus. Int J Rheum.Dis. 2019;22:434-442. doi: 10.1111/1756-185X.13387 (ア)

  19. Ueno M, Nakano K, Yoshinari H, Nakayamada S, Iwata S, Kubo S, Miyagawa I, Tanaka Y. An Autopsy Case with Cerebral Hemorrhaging Due to Disseminated Aspergillosis During Glucocorticoid Therapy for Overlap Syndrome of Systemic Lupus Erythematosus and Systemic Sclerosis. Intern Med. 2019;58:1023-1027. doi: 10.2169/internalmedicine.1226-18.

  20. Miyagawa I, Nakayamada S, Masahiro Kondo, Tanaka Y. Regulatory mechanism of the induction of regulatory T cells through growth factors released by human mesenchymal stem cells. Critical Reviews in Immunology. 2018. DOI:10.1615/CritRevImmunol.2018027821

  21. Miyazaki Y, Nakayamada S, Kubo S, Nakano K, Iwata S, Miyagawa I, Ma X, Trimova G, Sakata K, Tanaka Y. Th22 Cells Promote Osteoclast Differentiation via Production of IL-22 in Rheumatoid Arthritis. Front Immunol. 2018:10;9:2901. doi:10.3389/fimmu.2018.02901.

  22. Miyagawa I, Nakayamada S, Tanaka Y. Optimal Biologic Selection for Treatment of Psoriatic Arthritis: The approach to precision medicine. Current Rheumatol Rep. 2019;21:21. doi: 10.1007/s11926-019-0817-x.

  23. Satoh Y, Nakano K, Miyazaki Y, Nakayamada S, Fukuyo S, Kubo S, Miyagawa I, Yoshinari H, Saito K, Satoh M, Tanaka Y. The two case of acute acalculous cholecystitis associated with systemic lupus erythematosus (SLE) presented different clinical aspects. Modern Rheumatology Case Reports. 2019. DOI: 10.1080/24725625.2018.1549928

  24. Tanaka Y, Kubo S, Miyagawa I, Iwata S, Nakayamada S. Lymphocyte phenotype and its application to precision medicine in systemic autoimmune diseases. Semin Arthritis Rheum. 2019;48:1146-1150. DOI: 10.1016/j.semarthrit.2019.04.007.

  25. Miyagawa I, Nakano K, Iwata S, Nakayamada S, Saito K, Hanami K, Fukuyo S, Kubo S, Kawabe A, Miyazaki Y, Tanaka Y. Comparative study of corticosteroid monotherapy, and TNF inhibitors with or without corticosteroid in patients with refractory entero-Behcet’s disease. Arthritis Res Ther. 2019:21:151. doi.org/10.1186/s13075-019-1933-8

  26. Miyagawa I, Nakano K, Nakayamada S, Mori H, Okada Y, Saito K, Tanaka Y. A case of systemic lupus erythematosus in which Cushing’s syndrome caused by adrenal adenoma accidentally occurred during long-term maintenance therapy with corticosteroids. Modern Rheumatology Case Reports. 2019. DOI:10.1080/24725625.2019.1651488

  27. Yamauchi Y, Nakano K, Miyagawa I, Inaba Y, Nawata A, Sato N, Kumei S, Kawanami T, Yatera K, Tanaka Y. An Autopsy Case of a Patient with Systemic Sclerosis Who Developed Marked Pulmonary Hypertension Because of Pulmonary Tumor Thrombotic Microangiopathy Caused by Gastric Carcinoma. Modern Rheumatology Case Reports. 4.55-62. 2019

  28. Miyagawa I, Tanaka Y. Is precision medicine possible in rheumatic diseases? Lessons from selective use of targeted therapies in patients with psoriatic arthritis. Expert Rev Clin Immunol 16:199-206.2020

  29. Tanaka Y, Kuwana M, Fujii T, Kameda H, Muro Y, Fujio K, Itoh Y, Yasuoka H, Fukaya S, Ashihara K, Hirano D, Ohmura K, Tabuchi Y, Hasegawa H, Matsumiya R, Shirai Y, Ogura T, Tsuchida Y, Ogawa-Momohara M, Narazaki H, Inoue Y, Miyagawa I, Nakano K, Hirata S, Mori M. 2019 diagnostic criteria for mixed connective tissue disease: from the Japan Research Committee of the Ministry of Health, Labor, and Welfare for systemic autoimmune diseases. Mod Rheumatol 31:29-33.2021

  30. Miyagawa I, Nakano K, Nakayamada S, Iwata S, Hanami K, Fukuyo S, Kubo S, Kawabe A, Miyazaki Y, Inoue Y, Ueno M, Okubo N, Fujita Y, Tanaka Y. The additive effects of hydroxychloroquine to maintenance therapy with standard of care in patients with systemic lupus erythematosus. Int J Rheum.Dis.23:196-201.2020

  31. Funada M, Nakano K, Miyagawa I, Ueno M, Tanaka Y. Systemic lupus erythematosus with repeated protein-losing enteropathy resulting from different pathological conditions: a case report. Modern Rheumatology Case Reports. 4;229-232.2020

  32. Nakano K, Saito K, Nawata A, Hanami K, Kubo S, Miyagawa I, Fujino Y, Nakayamada S, Tanaka Y. Clinical aspects in patients with rheumatoid arthritis complicated with lymphoproliferative disorders without regression after methotrexate withdrawal and treatment for arthritis after regression of lymphoproliferative disorders. Mod Rheumatol.31:94-100.2021

  33. Kanda R, Nakano K, Miyagawa I, Iwata S, Nakayamada S, Tanaka Y. A case of bone destruction caused by chronic nonbacterial osteomyelitis (CNO) successfully repaired with a tumor necrosis factor-α (TNF-α) inhibitor, adalimumab. Modern Rheumatology Case Reports. 4:196-201.2020

  34. Ueno M, Nakano K, Miyagawa I, Tanaka Y. Five cases of IgG4-related diseases with nasal mucosa and sinus involvements. Intern Med. 59:1905-11. 2020

  35. Miyagawa I, Tanaka Y. The approach to precision medicine for the treatment of psoriatic arthritis. Immunol Med. 43:98-102.2020

  36. Miyazaki Y, Nakayamada S, Kubo S, Ishikawa Y, Yoshikawa M, Sakata K, Iwata S, Miyagawa I, Kazuhisa Nakano K, Tanaka Y. Favorable efficacy of rituximab in ANCA associated vasculitis patients with excessive B cell differentiation. Arthritis Res Ther. 2020:22:141.

  37. Ohkubo N, Nakano K, Miyagawa I, Tanaka Y. Mild Encephalitis/Encephalopathy with Reversible (ア) Splenial Lesions in SLE. Internal Med. 2020 doi: 10.2169/internalmedicine.4612-20.

  38. Miyagawa I, Kubo S, Tanaka Y. A wide perspective of targeted therapies for precision medicine in autoimmune diseases. Expert Rev Precis Med Drug Dev. 2020

  39. Ueno M, Miyagawa I, Nakano K, Iwata S, Hanami K, Fukuyo S, Kubo S, Miyazaki Y, Kawabe A, Yoshinari H, Nakayamada S, Tanaka Y. Effectiveness and Safety of Mepolizumab in Combination with Corticosteroids in patients with Eosinophilic Granulomatosis with Polyangiitis. Arthritis Res Ther 23;1-9.2021

  40. Ishikawa S, Miyagawa I, Kusanaga M, Abe T, Shiraishi A, Fujishima S, Ogura H, Saitoh D, Kushimoto S, Shiino Yasukazu, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi S, Takuma K, Hagiwara A, Yamakawa K, Takeyama N, Gando S; Mayumi T. Association of frailty on treatment outcomes among patients with suspected infection treated at emergency departments. European Journal of Emergency Medicine, 28:285-291.2021

  41. Miyazaki Y, Nakano K, Nakayamada S, Kubo S, Iwata S, Hanami K, Fukuyo S, Miyagawa I, Yamaguchi A, Kawabe A, Saito K, Tanaka Y. Serum TNFα levels at 24 hours after certolizumab pegol predict effectiveness at week 12 in patients with rheumatoid arthritis from TSUBAME study. Arthritis Res Ther 23:1-11.2021

  42. Ohkubo N, Iwata S, Nakano K, Miyagawa I, Hanami K, Fukuyo S, Miyazaki Y, Kawabe A, Nakayamada S, Tanaka Y. Efficacy and safety of high-dose of mycophenolate mofetil compared with cyclophosphamide pulse therapy as induction therapy in Japanese patients with proliferative lupus nephritis. Mod Rheumatol.2021. DOI: 10.1093/mr/roab113

  43. Miyagawa I, Tanaka Y. Dawn of precision medicine in psoriatic arthritis. Front Med (Lausanne). 682. 2022

  44. Ueno M, Miyagawa I, Kawabe A, Kusaka K, Nakayamada S, Tanaka Y. A patient with eosinophilic granulomatosis with polyangiitis successfully weaned from corticosteroids through remission induction therapy with mepolizumab. Modern Rheumatology Case Reports. 2022

  45. Todoroki Y, Kubo S, Nakano K, Miyazaki Y, Ueno M, Satoh-Kanda Y, Kanda R, Miyagawa I, Hanami K, Nakatsuka K, Saito K, Nakayamada S, Tanaka Y. Nailfold microvascular abnormalities are associated with a higher prevalence of pulmonary arterial hypertension in patients with MCTD. Rheumatology (Oxford) 2022

  46. Miyagawa I, Nakayamada S, Ueno M, Miyazaki Y, Iwata S, Kubo S, Sonomoto K, Anan J, Ohkubo N, Inoue Y, Tanaka Y. Impact of serum interleukin 22 as a biomarker for the differential use of molecular targeted drugs in psoriatic arthritis: A retrospective study. Arthritis Res Ther 2022

  47. Ueno M, Miyagawa I, Aritomi T, Kimura K, Iwata S, Hanami K, Fukuyo S, Kubo S, Miyazaki Y, Nakayamada S, Tanaka Y. Safety and Effectiveness of Mepolizumab Therapy in Remission Induction Therapy for Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Study. Arthritis Res Ther 2022

  48. Miyagawa I, Nakayamada S, Ueno M, Miyazaki Y, Ohkubo N, Inoue Y, Kubo S, Tanaka Y. Precision medicine based on the phenotypic differences in peripheral T helper cells in patients with psoriatic arthritis: One-year follow-up outcomes. Front Med (Lausanne) 2022

  49. Kusaka K, Miyagawa I, Kosaka S, Matsunaga S, Nakayamada S, Tanaka Y. A case of glucocorticoid-resistant adult Still’s disease compicated by pulmonary hypertension and interstitial lung disease. Modern Rheumatology Case Reports. 2022

  50. Ueno M. Miyagawa I, Miyazaki Y, Hanami K, Fukuyo S, Kubo S, Nakayamada S, Tanaka Y. Efficacy and Safety of Guselkumab and Adalimumab for Pustulotic Arthro-Osteitis and their Impact on Peripheral Blood Immunophenotypes. Arthritis Res Ther 2022

  51. Miyagawa I, Tanaka Y. Bimekizumab: a Humanized Monoclonal IgG1 Antibody for the Treatment of Psoriatic Arthritis. touchREVIEWS in RMD 2023 (in press)

  52. Kubo S, Miyazaki Y, Todoroki Y, Nagayasu A, Kanda R, Aritomi T, Matsunaga S, Ueno M, Miyagawa I, Sonomoto K, Hanami K, Nakayamada S, Tanaka Y. Generation-Dependent Retention Rates and Reasons for Discontinuation of Molecular Targeted Therapies in Patients with Rheumatoid Arthritis: From FIRST Registry. Rheumatol Ther. 2023. doi: 10.1007/s40744-023-00603-8.

  53. Miyazaki Y, Funada M, Nakayamada S, Sonomoto K, Tanaka H, Hanami K, Fukuyo S, Kubo S, Yamaguchi A, Miyagawa I, Todoroki Y, Ueno M, Tanaka Y. Safety and efficacy of anifrolumab therapy in systemic lupus erythematosus in real-world clinical practice: LOOPS registry. Rheumatology (Oxford). 2023 （in press）

  54. Schalter F, Azizov V, Frech M, Durholz K, Schmid E, Hendel A, Sarfati I, Maeda Y, Sokolova M, Miyagawa I, Focke K, Sarter K, van Baarsen LGM, Krautwald S, Schett G, Zaiss MM. CCL19-Positive Lymph Node Stromal Cells Govern the Onset of Inflammatory Arthritis via Tropomyosin Receptor Kinase. Arthritis Rheumatol. 2024;76:857-868.

  55. Funada M, Miyazaki Y, Nakayamada S, Sonomoto K, Kubo S, Miyagawa I, Tanaka H, Tanaka Y. CT informs detection and treatment options in rheumatoid arthritis complicated by pulmonary non-tuberculous mycobacterial disease from the FIRST registry. RMD Open. 2024;10:e004049.

  56. Miyazaki Y, Nakayamada S, Tanaka H, Hanami K, Fukuyo S, Kubo S, Miyagawa I, Yamaguchi A, Todoroki Y, Inoue Y, Ueno M, Tanaka Y. Comparison of anti-IL-6 receptor and JAK inhibitors in patients with rheumatoid arthritis from the real-world practice FIRST study. Rheumatology (Oxford). 2024:keae334. doi: 10.1093/rheumatology/keae334.

  57. Tsugita N, Miyagawa I, Nakayamada S, Nawata A, Kosaka S, Ueno M, Tanaka Y. Epstein-Barr Virus-Encoded RNA-Positive Lymphocytes in Bone Marrow and Lymph Nodes in an Autopsy Case of TAFRO Syndrome. Mod Rheumatol Case Rep. 2024 :rxae049. doi: 10.1093/mrcr/rxae049.

  58. Sakai H, Miyazaki Y, Nakayamada S, Kubo S, Hanami K, Fukuyo S, Yamaguchi A, Miyagawa I, Ueno M, Tanaka H, Todoroki Y, Ohkubo N, Funada M, Matsunaga S, Tanaka Y. Efficacy, safety, and optimal intervention of belimumab for proliferative lupus nephritis patients in real-world settings: LOOPS registry. Rheumatology (Oxford). 2024:keae495. doi: 10.1093/rheumatology/keae495.

  59. Kubo S, Miyazaki Y, Nishino T, Fujita Y, Kono M, Kawashima T, Ishigaki K, Kusaka K, Tanaka H, Ueno M, Satoh-Kanda Y, Inoue Y, Todoroki Y, Miyagawa I, Hanami K, Nakayamada S, Tanaka Y. Peripheral blood immunophenotypic diversity in patients with rheumatoid arthritis and its impact on therapeutic responsiveness. Ann Rheum Dis. 2024 :ard-2024-226228. doi: 10.1136/ard-2024-226228.

  60. Kusaka K, Miyazaki Y, Nakayamada S, Kubo S, Miyagawa I, Satoh-Kanda Y, Todoroki Y, Ueno M, Tanaka Y. The abundance of regulatory T cell subsets is associated with the clinical outcomes of sarcoidosis. Mod Rheumatol. 2024 Nov 14:roae106. doi: 10.1093/mr/roae106. Epub ahead of print. PMID: 39539229.

  61. Tsugita N, Miyagawa I, Ueno M, Takahashi M, Kosaka S, Nakayamada S, Tanaka Y：An autopsy of a patient with polyarteritis nodosa who developed fatal intestinal perforation accompanied by systemic multiple aneurysms and arterial thrombosis Modern Rheumatology Case Reports (in press)

  62. Kyuto Sonehara, Rei Watanabe, Yutaka Matsumura, Kaori Odomari, Saori Sakaue, Shinichi Namba, Tomomitsu Hirota, Noriko Arase, Yuumi Nakamura, Kimiko Nakajima, Takashi Okamoto, Rika Nishikawa, Kenichi Yamamoto, Ken Suzuki, Toshihiro Kishikawa, Ryuya Edahiro, Yuya Shirai, Tatsuhiko Naito, Noah Sasa, Yosuke Ishitsuka, Junichi Furuta, Kayo Kunimoto, Ikko Kajihara, Satoshi Fukushima, Hideaki Miyachi, Hiroyuki Matsue, Masahiro Kamata, Mami Momose, Ippei Miyagawa, Hiroaki Tanaka, Masanobu Ueno, Toshinori Bito, Hiroshi Nagai, Tetsuya Ikeda, Tatsuya Horikawa, Atsuko Adachi, Tsukasa Matsubara, Kyoko Ikumi, Emi Nishida, Biobank Japan Project, Koichi Matsuda, Nobuhiro Shojima, Ikuma Nakagawa, Yoshihide Asano, Shinichi Sato, Shinichi Imafuku, Yayoi Tada, Chikako Nishigori, Masatoshi Jinnin, Hironobu Ihn, Akihiko Asahina, Hidehisa Saeki, Toshimasa Yamauchi, Takashi Kadowaki, Tatsuyoshi Kawamura, Shinji Shimada, Ichiro Katayama, Koichiro Higasa, Emiko Noguchi, Shigetoshi Sano, Yoshiya Tanaka, Fumihiko Matsuda, Atsushi Kumanogoh, Mayumi Tamari, Manabu Fujimoto, Akimichi Morita, Yukinori Okada: Blood DNA virome associates with autoimmune diseases and COVID-19. Nat Genet(in press)

  63. Miyagawa I, Nakayamada S, Nohara H, Kosaka S, Ueno M, Tanaka Y. A case of Erdheim-Chester disease-a mimicker of IgG4-related disease and large vessel vasculitis. Mod Rheumatol Case Rep. 2024 Dec 17:rxae086.

  64. Miyagawa I, Nakayamada S, Saito K, Shimizu S, Hanami K, Ueno M, Tanaka Y. A case of newly onset rheumatoid arthritis successfully treated with methotrexate under the anti-retrovirus therapy against HIV infection. Mod Rheumatol Case Rep.rxaf011,2025

  65. Ueno M, Iwata S, Yamagata K, Todoroki Y, Sonomoto K, Nagayasu A, Miyagawa I, Kubo S, Miyazaki Y, Miyata H, Kanda R, Aritomi T, Nakayamada S, Tanaka Y. Induction of interleukin 21 receptor expression via enhanced intracellular metabolism in B cells and its relevance to the disease activity in systemic lupus erythematosus. RMD Open.10,e004567,2024

  66. Kanda R, Miyazaki Y, Nakayamada S, Fukuyo S, Kubo S, Miyagawa I, Yamaguchi A, Satoh-Kanda Y, Ohkubo N, Todoroki Y, Ueno M, Nagayasu A, Kusaka K, Sakai H, Matsunaga S, Nohara H, Tanaka Y. Effective Second-line b/tsDMARDs for Patients with Rheumatoid Arthritis Unresponsive to First-line b/tsDMARDs From the FIRST Registry.Rheumatol Ther.2025 (in press)

  67. Todoroki Y, Nakayamada S, Miyagawa I, Kubo S, Yoshioka K, Satoh M, Tanaka Y. Spontaneous Remission in a Patient with Anti-OJ Autoantibodies-positive Anti-synthetase Syndrome Following SARS-CoV-2 Infection and mRNA Vaccination: A Case Report. Intern Med. 2025 Mar 1. doi: 10.2169/internalmedicine.4852-24. Epub ahead of print. PMID: 40024740.

  68. Kubo S, Miyazaki Y, Tanaka H, Fujita Y, Sakai H, Ueno M, Todoroki Y, Satoh-Kanda Y, Miyagawa I, Nakayamada S, Tanaka Y. Transition of clinical remission rates with molecular targeted therapies in rheumatoid arthritis in Japan: insights from FIRST registry. Rheumatology (Oxford). 2025 May 13:keaf246. doi: 10.1093/rheumatology/keaf246. Epub ahead of print. PMID: 40358556.

  69. Nagayasu A, Miyazaki Y, Sonomoto K, Kubo S, Miyagawa I, Yamaguchi A, Tanaka H, Todoroki Y, Ueno M, Aritomi T, Fujita Y, Sakai H, Suzuki K, Nakayamada S, Tanaka Y. Influence of Rheumatoid Factors on the Efficacy of TNF Inhibitor Therapy in Patients with Rheumatoid Arthritis. Rheumatol Ther. 2025 May 16. doi: 10.1007/s40744-025-00769-3. Epub ahead of print. PMID: 40377857.

  70. Miyagawa I, Tanaka Y. Precision medicine using molecular-target drugs in psoriatic arthritis. Ther Adv Musculoskelet Dis. 2025 Jan 5;17:1759720X241311462. doi: 10.1177/1759720X241311462. PMID: 39776828; PMCID: PMC11701904.

  71. Sonehara K, Watanabe R, Matsumura Y, Mitsui Y, Ogawa Y, Odomari K, Sakaue S, Namba S, Komuro M, Edamoto M, Watanabe J, Hirota T, Arase N, Nakamura Y, Nakajima K, Okamoto T, Nishikawa R, Yamamoto K, Suzuki K, Kishikawa T, Edahiro R, Shirai Y, Naito T, Sasa N, Ishitsuka Y, Furuta J, Kunimoto K, Kajihara I, Fukushima S, Miyachi H, Matsue H, Kamata M, Momose M, Miyagawa I, Tanaka H, Ueno M, Bito T, Nagai H, Ikeda T, Horikawa T, Adachi A, Matsubara T, Nishida E; Biobank Japan Project; Matsuda K, Shojima N, Nakagawa I, Asano Y, Sato S, Imafuku S, Tada Y, Nishigori C, Jinnin M, Ihn H, Asahina A, Saeki H, Yamauchi T, Kadowaki T, Kawamura T, Shimada S, Katayama I, Higasa K, Noguchi E, Sano S, Tanaka Y, Matsuda F, Kumanogoh A, Tamari M, Satoh T, Fujimoto M, Morita A, Okada Y. Whole-genome sequencing reveals rare and structural variants contributing to psoriasis and identifies CERCAM as a risk gene. Cell Genom. 2025 Aug 19:100978. doi: 10.1016/j.xgen.2025.100978. Epub ahead of print. PMID: 40848718.

  72. Kusaka K, Kubo S, Nakayamada S, Miyagawa I, Miyazaki Y, Kanda Y, Todoroki Y, Ueno M, Kanda R, Setoyama K, Kataoka M, Tanaka Y. Association of exercise-induced pulmonary hypertension with nailfold capillary density in systemic sclerosis: a single-center retrospective observational study. Arthritis Res Ther. 2025 Aug 26;27(1):169. doi: 10.1186/s13075-025-03633-5. PMID: 40859364.1.

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