研究業績

原著論文

令和5(2023)年

The expression of matrix metalloproteinase-12 in the peritoneum of rats with continuous peritoneal dialysis.

Hasegawa E, Miyamoto T, Baba R, Kokubu K, Nakamura K, Kataoka M, Morimoto H.

Clin Exp Nephrol. 2023 Mar;27(3):203-210.

doi: 10.1007/s10157-022-02297-8.

The protein kinase R modifies gut physiology to limit colitis.

Yim HCH, Chakrabarti A, Kessler S, Morimoto H, Wang D, Sooraj D, Ahmed AU, de la Motte C, Silverman RH, Williams BR, Sadler AJ.

Front Immunol. 2023 Feb 17; 14: 1106737.

doi: 10.3389/fimmu.2023.1106737

令和4(2022)年

Expression of T-Type Voltage-Gated Calcium Channel in the Cilia of Human Nasal Epithelial Cells

Nguyen TN, Suzuki H, Baba R, Yoshida Y, Ohkubo JI, Wakasugi T, Kitamura T.

Int Arch Allergy Immunol. 2022; 183(6): 579-90.

doi: 10.1159/000521765.

Pentacyclic triterpenoid ursolic acid induces apoptosis with mitochondrial dysfunction in adult T-cell leukemia MT-4 cells to promote surrounding cell growth.

Shen M, Wang D, Sennari Y, Zeng Z, Baba R, Morimoto H, Kitamura N, Nakanishi T, Tsukada J, Ueno M, Todoroki Y, Iwata S, Yonezawa T, Tanaka Y, Osada Y, Yoshida Y.

Med Oncol. 2022 Jun 8; 39(8):118.

doi: 10.1007/s12032-022-01707-x.

Paneth cell maturation is related to epigenetic modification during neonatal–weaning transition

Baba R, Kokubu K, Nakamura K, Fujita M, Morimoto H.

Histochem Cell Biol. 2022 Jul;158(1):5-13.

doi: 10.1007/s00418-022-02110-3.

Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats.

Nishimura H, Yoshimura M, Shimizu M, Sanada K, Sonoda S, Nishimura K, Baba K, Ikeda N, Motojima Y, Maruyama T, Nonaka Y, Baba R, Onaka T, Horishita T, Morimoto H, Yoshida Y, Kawasaki M, Sakai A, Muratani M, Conway-Campbell B, Lightman S, Ueta Y.

Commun Biol. 2022 Sep 5;5(1):907.

doi: 10.1038/s42003-022-03879-8.

オルガノイド

森本景之

臨床精神薬理. 2022 Sep 25(9): 1041-2.

The expression of matrix metalloproteinase-12 in the peritoneum of rats with continuous peritoneal dialysis.

Hasegawa E, Miyamoto T, Baba R, Kokubu K, Nakamura K, Kataoka M, Morimoto H.

Clin Exp Nephrol. 2022 Nov 12.

doi: 10.1007/s10157-022-02297-8. Online ahead of print.PMID: 36371578

令和3(2021)年

A Simple Preparation Method for CLEM Using Pre-Embedding Immunohistochemistry with a Novel Fluorescent Probe and Stable Embedding Resin

Kanemaru T, Kondo T, Nakamura K, Morimoto H, Nishi K, Isobe SI.

Microscopy (Oxf) .2021 Aug 9; 70 (4): 368-374.

doi: 10.1093/jmicro/jmicro/dfab005.

Trehalose alleviates oxidative stress-mediated liver injury and Mallor-Denk body formation via activating autophagy in mice

Honma Y, Sato-Morita M, Katsuki Y, Mihara H, Baba R, Hino K, Kawashima A, Ariyasu T, Harada M.

Med Mol Morphol. 54(1): 41-51 (2021)doi: 10.1007/s00795-020-00258-2. Epub 2020 Jun 25.

doi: 10.1007/s00795-020-00258-2. Epub 2020 Jun 25

令和2(2020)年

Particulate Matter, Asian Sand Dust Delays Cyclophosphamide-induced Type 1 Diabetes in NOD Mice.
Morita K, Wang D, Baba R, Morimoto H, Song Y, Kanazawa T, Yoshida Y.

Immunol Invest. 49(7): 698-710 (2020)doi: 10.1080/08820139.2019.1699569.

令和1(2019)年

Efficacy of a novel mixture of substances derived from food and food additives for controlling Dermanyssus gallinae (Mesostigmata: Dermanyssidae).
Odaka M, Matsuo K, Ogino K, Kanazawa T, Baba R, Sakata Y, Asada K, Kasa S, Takai K, Maeda K. Applied Entomology and Zoology 54(1): 31-8 (2019)

Calmodulin and protein kinases A/G mediate ciliary beat response in the human nasal epithelium.
Do BH, Nguyen TN, Baba R, Ohbuchi T, Ohkubo JI, Kitamura T, Wakasugi T, Morimoto H, Suzuki H
Int Forum Allergy Rhinol. 9(11): 1352-9 (2019) doi: 10.1002/alr.22442.

平成30（2018)年

Trehalose activates autophagy and decreases proteasome inhibitor-induced endoplasmic reticulum stress and oxidative stress-mediated cytotoxicity in hepatocytes.Honma Y, Sato-Morita M, Katsuki Y, Mihara H, Baba R, Harada M.Hepatol Res. 48(1): 94-105 (2018)doi: 10.1111/hepr.12892.

Pre-embedding correlative light and electron microscopy using FluoroNanogold combined gold nanoparticle and new fluorescent dye, Fluolid NSL Orange.Kanemaru T,　Kondo　T, Nishi　K,　Yazumi T, Nakamura K, Morimoto H, Isobe S.Microscopy. 67(suppl 2): i30 (2018)https://doi.org/10.1093/jmicro/dfy085

平成29（2017）年

PKR regulates LPS-induced osteoclast formation and bone destruction in vitro and in vivo.
Teramachi J, Inagaki Y, Shinohara H, Okamura H, Yang D, Ochiai K, Baba R, Morimoto H, Nagata T, Haneji T. Oral Dis. 23(2):181-188 (2017) doi: 10.1111/odi.12592.

Role of protein phosphatase 2A in osteoblast differentiation and function. Okamura H, Yoshida K, Morimoto H, Teramachi J, Ochiai K, Haneji T, Yamamoto A. J Clin Med 6(3): 23 (2017) doi: 10.3390/jcm6030023.

回腸吸収上皮細胞の形態および機能の変化. 馬場良子, 國分啓司, 森本景之, 藤田　守.顕微鏡 52(1): 35-39 (2017)

平成28（2016）年

Ishimatsu N, Miyamoto T, Ueno H, Hasegawa E, Kuma A, Fujimoto Y, Bando K, Nakamata J, Furuno Y, Serino R, Baba R, Morimoto H, Doi Y, Tamura M, Otsuji Y.
High glucose concentration-induced expression of pentraxin-3 in a rat model of continuous peritoneal dialysis.
Histol Histopathol. 31(11):1251-8 (2016) doi: 10.14670/HH-11-756.

Sakuma Y, Arita K, Baba R, Kumagai N, Fujita M. Keimyung
Morphological study: Application to breastfeeding nursing, influence of supplemental feeding at the early neonatal stage –Application to breastfeeding nursing -.
Journal of Nursing Science, 19(3): 63-69 (2016)

Miyagawa K, Oe S, Homma Y, Izumi H, Baba R, Harada M.
Lipid-induced endoplasmic reticulum stress impairs selective autophagy at the step of autophagosome-lysosome fusion in hepatocytes.
The American Journal of Pathology, 186(7): 1861-73 (2016) doi: 10.1016/j.ajpath.2016.03.003.

Yang D, Okamura H, Morimoto H, Teramachi J, Haneji T.
Protein phosphatase 2A Cα regulates proliferation, migration, and metastasis of osteosarcoma cells.
Lab Invest. 96(10): 1050-62 (2016) doi: 10.1038/labinvest.2016.82.

平成27（2015）年

Jahan MR, Kokubu K, Islam MN, Matsuo C, Yanai A, Wroblewski G, Fujinaga R, Shinoda K.
Species differences in androgen receptor expression in the medial preoptic and anterior hypothalamic areas of adult male and female rodents.
Neuroscience, 284, 943–961 (2015) doi: 10.1016/j.neuroscience.2014.11.003. Epub 2014 Nov 13

Takahashi H, Baba R, Ishimatsu N, Morimoto H, Fujita M.
Morphological analysis of small intestinal organoids.
The Journal of Physiological Sciences. 65(Supplement 1): S164 (2015)

Nemoto J, Jahan MR, Islam MN, Kokubu K, Yanai A, Wroblewski G, Fujinaga R, Shinoda K.
Species difference in expression and localization of androgen receptor in the suprachiasmatic nuclei of normal and hormone-manipulated adult rats and mice.
The Journal of Physiological Sciences. 65(Supplement 1): S170 (2015)

Teramachi J, Morimoto H, Okamura H, Haneji T.
Critical role of PKR in TNF-α-induced osteoclastogenesis.
The Journal of Physiological Sciences. 65(Supplement 1): S186 (2015)

Ishimatsu N, Miyamoto T, Morimoto H, Nakamata J, Baba R, Otsuji Y, Tamura M.
Pentraxin3 expression in a rat model of peritoneal dialysis.
The Journal of Physiological Sciences. 65(Supplement 1): S218 (2015)

Islam MN, Fujinaga R, Takeshita Y, Yanai A, Jahan MR, Kokubu K, Wroblewski G, Shinoda K.
Localization of huntingtin-associated protein 1-immunoreactive stigmoid bodies in the spinal cord of adult rat.
The Journal of Physiological Sciences. 65(Supplement 1): S282 (2015)

Morimoto H.
My Profile and Future Approach.
Kaibogaku Zasshi. 90(3): 15-6 (2015)

平成26（2014）年

Nguyen KH, Suzuki H, Ohbuchi T, Wakasugi T, Koizumi H, Hashida K, Baba R, Morimoto H, Doi Y.
Possible participation of acidic pH in bone resorption in middle ear cholesteatoma.
Laryngoscope. 124(1):245-50 (2014)

Sakuma Y, Baba R, Arita K, Morimoto H, Fujita M.
Food allergens are transferred intact across the rat blood-placental barrier in vivo.
Med Mol Morphol. 47(1):14-20 (2014)

Fukudome I, Kobayashi M, Dabanaka K, Maeda H, Okamoto K, Okabayashi T, Baba R, Kumagai N, Oba K, Fujita M, Hanazaki K.
Diamine oxidase as a marker of intestinal mucosal injury and the effect of soluble dietary fiber on gastrointestinal tract toxicity after intravenous 5-fluorouracil treatment in rats.
Med Mol Morphol. 47(2):100-7 (2014)

Liu MS, Wang D, Morimoto H, Yim HC, Irving AT, Williams BR, Sadler AJ.
Molecular dynamics reveal a novel kinase-substrate interface that regulates protein translation.
J Mol Cell Biol. 6(6):473-85 (2014)

平成25（2013）年

Morimoto H, Baba R, Haneji T, Doi Y.
Double-stranded RNA-dependent protein kinase regulates insulin-stimulated chondrogenesis in mouse clonal chondrogenic cells, ATDC-5.
Cell Tissue Res. 351(1):41-7 (2013)

Haneji T, Hirashima K, Morimoto H.
Okadaic acid activates the PKR pathway and induces apoptosis through PKR stimulation in MG63 osteoblast-like cells.
Int J Oncol. 42(6): 1904-10 (2013)

Aoki S, Udo K, Morimoto H, Ikeda S, Takezawa T, Uchihashi K, Nishijima-Matsunobu A, Noguchi M, Sugihara H, Toda S.
Adipose tissue behavior is distinctly regulated by neighboring cells and fluid flow stress: a possible role of adipose tissue in peritoneal fibrosis.
J Artif Organs. 16(3): 322-31 (2013)

平成24（2012）年

Haneji T, Teramachi J, Hirashima K, Morimoto H.
Interaction of protein phosphatase 1δ with nucleophosmin in human osteoblastic cells.
Acta Histochemica et Cytochemica 45(1): 1-7 (2012)

Irving AT, Wang D, Vasilevski O, Latchoumanin O, Kozer N, Clayton AH, Szczepny A, Morimoto H, Xu D, Williams BR, Sadler AJ.
Regulation of actin dynamics by protein kinase R control of gelsolin enforces basal innate immune defense.
Immunity, 36(5): 795-806 (2012)

森本景之，馬場良子
細胞性ストレスとeIF-2αキナーゼ（総説）
産業医科大学雑誌, 34(4): 331-8 (2012)

Islam MN, Fujinaga R, Yanai A, Jahan MR, Takeshita Y, Kokubu K, Shinoda K.
Characterization of the "sporadically lurking HAP1-immunoreactive (SLH) cells" in the hippocampus, with special reference to the expression of steroid receptors, GABA, and progenitor cell markers.
Neuroscience 210: 67-81 (2012)

平成23（2011）年

Kashiwagi E, Izumi H, Yasuniwa Y, Baba R, Doi Y, Kidani A, Arao T, Nishio K, Naito S, Kohno K.
Enhanced expression of nuclear factor I/B in oxaliplatin-resistant human cancer cell lines.
Cancer Science, 102 (2): 382-6 (2011)

Baba R, Sakaguchi A, Nakamata J, Morimoto H, Doi Y, Fujita M.
Relationship between endosomal system and microtubules in absorptive cells of suckling rat ileum.
Journal of Physical Sciences, 61 (Suppl. 1): S254 (2011)

Kumagai N, Baba R, Sakuma Y, Arita K, Shinohara M, Kourogi M, Fujimoto S, Fujita M.
Origin of apical transcytic membrane system in jejunal absorptive cells of neonates.
Med Mol Morphol, 44 (2): 71-8 (2011)

Fujinaga R, Takeshita Y, Yoshioka K, Nakamura H, Shinoda S, Islam MN, Jahan MR, Yanai A, Kokubu K, Shinoda K.
Intracellular colocalization of HAP1/STBs with steroid hormone receptors and its enhancement by a proteasome inhibitor.
Exp Cell Res. 317(12): 1689-700 (2011)

Takeshita Y, Fujinaga R, Kokubu K, Islam MN, Jahan MR, Yanai A, Kakizuka A, Shinoda K.
Interaction of ataxin-3 with huntingtin-associated protein 1 through Josephin domain.
Neuroreport 22(5): 232-8 (2011)

平成22（2010）年

Kudo H, Doi Y, Fujimoto S.
Expressions of the multidrug resistance-related proteins in the rat olfactory epithelium: A possible role in the phase 3 xenobiotic metabolizing function.
Neuroscience Letters, 468 (2): 98-101 (2010)

Miyamoto T, Tamura M, Kabashima N, Serino R, Shibata T, Furuno Y, Miyazaki M, Baba R, Sato N, Doi Y, Okazaki M, Otsuji Y.
An integrin‐activating peptide, PHSRN, ameliorates inhibitory effects of conventional peritoneal dialysis fluids on peritoneal wound healing.
Nephrol Dial Transplant, 25 (4): 1109-19 (2010)

Sato N, Morimoto H, Baba R, Nakamata J, Doi Y, Yamaguchi K.
Functional expression of double-stranded RNA-dependent protein kinase in rat intestinal epithelial cells.
J Cell Biochem, 110 (1): 104-11 (2010)

Asahi J, Kamo H, Baba R, Doi Y, Yamashita A, Murakami D, Hanada A, Hirano T.
Bisphenol A induces endoplasmic reticulum stress-associated apoptosis in mouse non-parenchymal hepatocytes.
Life Sciences, 87 (13-14): 431-8 (2010)

Teramachi J, Morimoto H, Baba R, Doi Y, Hirashima K, Haneji T.
Double stranded RNA-dependent protein kinase is involved in osteoclast differentiation of RAW264.7 cells in vitro.
Exp Cell Res, 316 (19): 3254-62 (2010)

藤田　守、馬場良子、熊谷奈々
新生児期・乳飲期・離乳期における腸の吸収機構
顕微鏡、45 (4): 229-36 (2010)

平成21（2009）年

Kudo H, Doi Y, Ueda H, Kaeriyama M.
Molecular characterization and histochemical demonstration of salmon olfactory marker protein in the olfactory epithelium of lacustrine sockeye salmon (Oncorhynchus nerka).
Comp Biochem Physiol A Mol Inteqr Physiol, 154 (1): 142-50 (2009)

Fujinaga R, Takeshita Y, Uozumi K, Yanai A, Yoshioka K, Kokubu K, Shinoda K.
Microtubule-dependent formation of the stigmoid body as a cytoplasmic inclusion distinct from pathological aggresomes.
Histochem Cell Biol, 132(3): 305-18 (2009)

著書

令和4(2022)年

3節 薄切　幸喜　富、立花利公、馬場良子、盛一伸子、山口正視．4節 試料支持　山口正視、福嶋球琳男、幸喜　富、馬場良子、盛一伸子．新・電顕入門ガイドブック 電顕入門ガイドブック改訂第3版 ［公社］日本顕微鏡学会 電子顕微鏡技術認定委員会 編 p. 46～92 (2022)

令和1(2019)年

灌流固定法　國分啓司、馬場良子、森本景之　第30回 知る 使う 考える 電子顕微鏡活用法　電顕サマースクール in 北九州2019　第30回 電顕サマースクール実行委員会　p. 115-119（2019）

平成30（2018）年

超薄切片法　馬場良子、國分啓司、横山　満、森本景之、藤田　守　電子顕微鏡 基礎技術チュートリアル　医学生物学 電子顕微鏡基礎：医・生物分野でのゼロから聞ける、電子顕微鏡試料作成と観察の基礎の基礎！ p. 32-39（2018）

平成28（2016）年

馬場良子、國分啓司、横山　満、森本景之、藤田　守
超薄切片法
In:第27回 電顕サマースクール2016　超明解 電子顕微鏡法入門講座「1枚の写真に尽くす基礎原理と方法論」p. 57-66（2016）

平成26（2014）年

藤田　守、馬場良子、熊谷奈々、森本景之
あなたの知らない透過型電子顕微鏡TEMの世界　～生命の秘密を暴こう～
In: 第25回 電顕サマースクール2014　テキスト　pp. 2-19（2014）

横山　満、馬場良子、森本景之
一般的なSEM試料作製法と観察
In: 第25回 電顕サマースクール2014　実習用テキスト　pp. 25-33（2014）

森本景之、馬場良子
灌流固定法
In: 第25回 電顕サマースクール2014　実習用テキスト　pp. 34-8（2014）

平成25（2013）年

藤田　守、馬場良子、熊谷奈々、森本景之
透過型電子顕微鏡で「生命のカラクリ」を覗こう　～医学・生物学の受講者の皆様へ～
In: 第26回 電子顕微鏡技術研修会　夏の学校in 北九州　テキスト　pp. 1-4（2013）

森本景之、馬場良子
灌流固定法
In: 第26回 電子顕微鏡技術研修会　夏の学校in 北九州　テキスト　pp. 51-4（2013）

平成23（2011）年

山下修二、勝又　修、土肥良秋
4節　免疫電顕法
In: 電顕入門ガイドブック改訂版 （社）日本顕微鏡学会電子顕微鏡技術認定委員会（編）
国際文献印刷社、東京、pp. 77-90 (2011)

森本景之、土肥良秋、藤本　淳
第1章　6. 細胞傷害「化学物質による細胞毒性」
In: 病気の分子形態学、日本臨床分子形態学会（編）、学際企画、東京、pp. 26-8 (2011)

藤田　守、馬場良子、熊谷奈々、坂口　彩
第2章　1-5．消化管と栄養
In: 病気の分子形態学、日本臨床分子形態学会（編）、学際企画、東京、pp.91-4 (2011)

平成22（2010）年

1. 藤田　守、馬場良子、熊谷奈々
TEMの基礎　透過型電子顕微鏡（Transmission Electron Microscope: TEM）で生命を観る
In: 第21回電顕サマースクールテキスト、第21回電顕サマースクール実行委員会、福岡、pp. 1-22 (2010)